Review on Helicobacter pylori associated Diseases

Shahrazad H. Muhi; Farah Badri Abed; Nada H. Bedair; Saba R. Jaafar; Sahar M. Ibrahim; Dunya Abdullah Mohammed; Omar A. Mahmoud; Ruaa H. Ali; Mohammed Ayad Hameed; Luma Mahmood Edan

doi:10.47419/bjbabs.v5i3.307

Authors

SHahrazad H. Muhi Higher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, Iraq. https://orcid.org/0009-0004-1148-3762
Farah Badri Abed Higher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, Iraq. https://orcid.org/0000-0003-1356-2304
Nada H. Bedair Higher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, Iraq. https://orcid.org/0000-0003-1852-0154
Saba R. Jaafar Higher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, Iraq. https://orcid.org/0009-0006-5576-6902
Sahar M. Ibrahim Higher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, Iraq. https://orcid.org/0009-0005-6638-9498
Dunya Abdullah Mohammed Higher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, Iraq. https://orcid.org/0009-0009-0541-8194
Omar A. Mahmoud Higher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, Iraq. https://orcid.org/0009-0005-6884-9398
Ruaa H. Ali Higher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, Iraq. https://orcid.org/0009-0003-1501-9871
Mohammed Ayad Hameed Higher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, Iraq. https://orcid.org/0009-0000-8621-3696
Luma Mahmood Edan Higher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, Iraq. https://orcid.org/0000-0001-5781-8768

DOI:

https://doi.org/10.47419/bjbabs.v5i3.307

Keywords:

H. pylori, Gastric Disease, Extra Gastric Manifestations

Abstract

One of the most common and enduring bacterial infections globally, Helicobacter pylori (H. pylori) infects almost half of the world’s population. The bacterium is described as a spiral microaerophilic gram-negative bacterium; it is commonly found in the stomach and can cause several categories of gastrointestinal conditions, such as gastritis, peptic ulcers, and in some circumstances, stomach cancer. There is also a growing knowledge that chronic H. pylori infection may be associated with an increased danger of extra-gastric disease that includes host iron deficiency anemia, and cardiovascular, autoimmune, metabolic, neurological, and dermatological diseases. In this article, we examined the virulence factors of H. pylori and its correlation to gastrointestinal diseases, as well as the bacterium’s potential involvement in extra-gastric diseases such as iron and vitamin B12 deficiency, in addition to neurological, cardiovascular, inflammatory bowel, and diabetes mellitus disorders.

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