Baghdad Journal of Biochemistry and Applied Biological Sciences <p> </p> <p>Baghdad Journal of Biochemistry and Applied Biological Sciences (BJB-ABS) published by College of Medicine, Al- Nahrain University provides quarterly publication of articles in all areas related to Biochemistry, Analytical Biochemistry, Clinical Chemistry, Pharmaceutical Chemistry, Medical Chemistry, Environmental Chemistry, Physical Biochemistry, Molecular Biology. Baghdad Journal of Biochemistry and Applied Biological Sciences welcomes the submission of manuscripts that meet the general criteria of significance and scientific excellence. Papers will be published approximately 7 days after acceptance.</p> <p>The “Baghdad Journal of Biochemistry and Applied Biological Sciences” is using the Open Journal System for online manuscript submission, review, and tracking. Editorial board members of the journal or outside experts review manuscripts; at least two independent reviewers approval followed by the editor is required for the acceptance and publication of any citable manuscript.</p> en-US <p>The authors retain the copyright of their manuscript by submitting the work to this journal, and all open access articles are distributed under the terms of the Creative Commons Attribution License (<a href="">Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) </a>), which permits unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited. </p> (Managing Editor of BJB-ABS) (Dr. Qasim S. Haraj ) Sat, 20 Feb 2021 18:27:30 +0000 OJS 60 Serum and urinary soluble alpha klotho levels in patients with Chronic kidney disease <p><strong>Abstract </strong></p> <p><strong>Background</strong>: Chronic kidney disease is an epidemic global health problem that leads to death. To prevent any disease progression and treatment, the diagnosis must be made in the early stage by studying renal damage. Klotho is a protein found in many organs of the human body, but it is mainly abundant in the kidney. This study aimed to evaluate klotho's clinical significance as an additional biomarker for diagnosing chronic kidney disease in its early stages. </p> <p><strong>Method</strong>s: One hundred subjects were included in this study to measure their serum and urinary klotho. Forty patients with chronic kidney disease (pre-dialysis) and sixty normal subjects were enrolled in this study. Serum and urinary klotho were determined using the ELISA technique in addition to other renal function tests.</p> <p><strong>Results : </strong>Serum and urinary alpha klotho were decreased in CKD patients when it compared with control subjects. A positive correlation was found between serum creatinine and urinary alpha klotho in the patients' group.</p> <p><strong>Conclusion:</strong> Serum and Urinary alpha klotho levels were decreased significantly in patients with chronic kidney disease compared with healthy controls.</p> Khalid Jamal Al-Jewari, Rayah S. Baban , Jawad Kadhim Manuti Copyright (c) 2021 Khalid Jamal Al-Jewari, Rayah S. Baban , Jawad Kadhim Manuti Sun, 04 Apr 2021 00:00:00 +0000 Herbal Medicine as an Alternative Method to Treat and Prevent COVID-19 <p><strong>Background:</strong> The current outbreak of the serious respiratory syndrome disease COVID-19 has resulted from a novel coronavirus (SARS-CoV-2).&nbsp; This infectious disease was classified as a pandemic by the World Health Organization (WHO) because it is threatening public health and life worldwide. Recently, restrictions in many countries are applied to detect the infected individuals and isolate them, in addition to attempts to find appropriate treatments that can help decrease the severe symptoms of the disease. Regardless of the conduced efforts, the number of reported cases of coronavirus infections is still growing up. Yet, no medication or vaccine was approved to prevent and/or treat people from this coronavirus, though many researches from academic groups and medication companies are still ongoing.</p> <p><strong>Objective:</strong> This review aims to summarize the possible herbs and plants from the natural herbal medicine along with western medicine, which could assist treat or protect people from COVID-19.</p> <p>Understanding the infection rules, clarifying the pathogenic mechanisms, and detecting the appropriate medication treatment could improve the development of the essential treatment and prevention methods.&nbsp;</p> <p><strong>Conclusion:</strong> Since the finally-approved drug for this virus is still absent and a sharp increase in infection numbers is taking place, it became urgent to present possible alternatives, such as the Chinese herbal medicines, in a trail to cure SARS-CoV-2.</p> Mohammed Kadhom, Ahmed Nadhmi Al-Doori , Dina S. Ahmed, Emad Yousif Copyright (c) 2021 Mohammed Kadhom, Ahmed Nadhmi Al-Doori , Dina S. Ahmed, Emad Yousif Sat, 20 Feb 2021 00:00:00 +0000 The antioxidant, antimicrobial, and clinical effects with elemental contents of Pomegranate (Punica Granatum) Peel Extraction: A Review <p><strong>Background:</strong> Pomegranate belongs to the family of Punicaceae. It has deciduous shrubs. Pomegranate is generally cultivated in Afghanistan, China, Iran, India, Pakistan, USA.</p> <p><strong>Objective:</strong> This study aimed to review the pomegranate peels for exploring their importance in the field of health.</p> <p><strong>Results:</strong> This review showed that Pomegranate is used as food and plays a vital role in the medicinal field. Because pomegranate fruit and its peel extraction contain various compounds like antioxidants, phenolic Acid, Flavonoids, Tannins etc., that have been found very effective in the health field. Due to the presence of antioxidants and other active compounds, pomegranates' peel is imperative for the betterment of human health. Besides, various medicines such as antidiarrheal medicine may be prepared from the peel extract of Pomegranate. Peel extract can act against various microbes such as Klebsiella pneumonia and Staphylococcus epidermidis, Bacillus subtilis, Klebsiella pneumoniae, Salmonella typhi, E. coli, S. aureus etc. The pomegranate strip and root remove have been accounted for in creatures to diminish blood glucose activity.</p> <p><strong>Conclusion:</strong> It concludes that further research is needed to explore the hidden characteristics of pomegranate peel.</p> Abdul Qahir , Attiq-Ur-Rehman Kakar, Naqeebullah Khan, Samiullah, Abdul Hakeem, Rehana Kamal, Fazal-Ur-Rehman Copyright (c) 2021 Abdul Qahir , Attiq-Ur-Rehman Kakar, Naqeebullah Khan, Samiullah, Abdul Hakeem, Rehana Kamal, Fazal-Ur-Rehman Mon, 08 Mar 2021 00:00:00 +0000